Assuming you acquire a legitimate 5th or 6th edition PDF (legally via purchase or institutional access), here is the structure that made the book famous:
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– Source: Liver (canalicular membrane), bone (osteoblasts), placenta, intestine. – Elevated in: Cholestasis (intrahepatic or extrahepatic), infiltrative liver disease (e.g., sarcoid, metastases), pagetic bone disease, growing children (physiologic). – Discrimination: GGT rise with ALP suggests hepatobiliary origin; normal GGT with high ALP suggests bone source. – Drug effect: Phenytoin, phenobarbital can induce ALP (isolated, asymptomatic). Assuming you acquire a legitimate 5th or 6th