If you are trying to patch Adobe Photoshop 2023 or 2024, It is strictly for the 2020 generation of apps. Using the wrong version leads to application crashes, "licensing errors," or the dreaded "Unlicensed App" pop-up.
Use the "Pop-up" or "CC Guide" buttons within the tool to block host files and disable the Adobe Genuine Service. A Quick Word of Caution genp universal patch 350