DirectX 12 is highly sensitive to hardware instability. If you have manually overclocked your GPU using MSI Afterburner or similar tools, even a stable overclock in other games might cause a D3D Fatal Error in RE Engine titles.
The game stores compiled shaders on your drive. If these corrupt, you get the "Hung" error. Renderdevicedx12.cpp Fatal D3d Error Resident Evil 2
Before we fix it, let's briefly understand what the error means. DirectX 12 is highly sensitive to hardware instability
: Some users found that increasing the Windows Virtual Memory (Page File) to 8192 MB (8GB) resolved the crash. If these corrupt, you get the "Hung" error
Resident Evil 2 defaults to DX12 for ray tracing. However, the game is notoriously unstable with DX12 on many cards. The game’s files support DX11, even if the menu hides it.
Switch from "Full Screen" to "Borderless Window" in graphics settings. Enable Hardware Accelerated GPU Scheduling: