For the most up-to-date experience, it is highly recommended to use the latest nightly or PCSX2 2.0+ builds rather than outdated 1.6.0 versions.
: Reduces the load on the main Emotion Engine (EE) thread, often dropping its usage significantly (e.g., from 80% down to 50%) to allow smoother gameplay.
Meta: MTVU compatibility issues #1669 - PCSX2/pcsx2 - GitHub 20 Nov 2016 —
While MTVU is a "holy grail" for performance in 95% of games, a few titles don't play nice with it. Massive speed boosts in CPU-heavy games like Shadow of the Colossus Ratchet & Clank