The supporting cast, including as the concerned family driver and Ehra Madrigal as the skeptical sister-in-law, provide the audience’s rational perspective—the voices begging Karen to leave before it is too late.

As the story unfolds, the family's past is slowly revealed, including Doña Victoriana's complicated relationship with her late husband and her children's struggles with their own relationships and careers. The family is forced to confront their demons and learn to accept each other for who they are.

Raymond moves Karen into his family’s massive, isolated estate—simply referred to as "The Casa." From the moment she enters, Karen feels a hostile presence. She hears children’s laughter in empty halls, finds her belongings moved, and suffers from terrifying nightmares involving a faceless woman in white.